No question in heavy duty applications such as racing or heavy hauling (motor homes, etc..), that one will see a difference in wear between premium synthetic oils and standard dino oils. But for the average person motoring down the highway, does it make a difference?
There was a story a few years ago about a guy who put one million miles (all highway driving) on his 96 Chevy pickup using standard Penzoil of all things. Eight sets of tires and a few transmissions, but he never touched the engine. Penzoil bought him a new truck and used his for advertising.
I suspect for most of us, other parts of our bikes and cars will fail long before the engine wears out on dino oil.